SCHEMBL7689433

SCHEMBL7689433

C#CC(C)Oc1cc(N)c(F)cc1Cl

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.36
PPOX P50336 1/20 0.33
MAOA P21397 3/20 0.33
GAA P10253 1/20 0.33
MET P08581 1/20 0.30
CSNK2A1 P68400 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9769730 0.85 NPC1 (0.52) NPC1MAOAGAACSNK2A1
SCHEMBL9769676 0.84 NPC1 (0.36) NPC1PPOXGAAMETCSNK2A1
SCHEMBL7529711 0.84 SRC (0.33)
SCHEMBL4678114 0.82 PPOX (0.45) NPC1PPOXGAACSNK2A1
SCHEMBL9769674 0.81 MAOA (0.36) NPC1PPOXMAOAGAACSNK2A1
SCHEMBL8879333 0.79 NPC1 (0.43) NPC1PPOXGAAMETCSNK2A1
SCHEMBL10811265 0.76 NPC1 (0.38) NPC1PPOXGAA
SCHEMBL8599131 0.76 SLC2A1 (0.39) NPC1PPOXGAACSNK2A1
SCHEMBL8602842 0.76
SCHEMBL8485419 0.76 ALDH1A1 (0.31) PPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6337417-B1 IMIDOYL CHLORIDE DERIVATIVE CHEMICAL INTERMEDIATES THAT ARE NOT HARMFUL TO CROPS CENTRAL GLASS CO., LTD. (JP) 2002-01-08 US disclosed
EP-0659735-B1 PROCESS FOR PRODUCING ANILINE DERIVATIVE SAGAMI CHEM RES (JP) 1999-01-13 EP disclosed
US-5801122-A N-phenyltetrahydrophthalamic acid derivatives, methods of producing same, and herbicides containing same as effective components CENTRAL GLASS CO., LTD. (JP) 1998-09-01 US disclosed
EP-0626370-B1 Process for producing aromatic isothiocyanate derivatives SUMITOMO CHEMICAL CO (JP) 1998-02-11 EP disclosed
US-5639915-A Process for the production of aniline derivatives SAGAMI CHEMICAL RESEARCH CENTER (JP) 1997-06-17 US disclosed
EP-0741131-A1 N-PHENYLTETRAHYDROPHTHALAMIC ACID DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT CENTRAL GLASS COMPANY, LIMITED (JP) 1996-11-06 EP disclosed
EP-0496347-B1 Methods of preparing fluorobenzene derivatives and related compounds SAGAMI CHEM RES (JP) 1996-09-04 EP disclosed
EP-0659735-A1 PROCESS FOR PRODUCING ANILINE DERIVATIVE SAGAMI CHEMICAL RESEARCH CENTER (JP) 1995-06-28 EP disclosed
EP-0650957-A1 ANILINE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1995-05-03 EP disclosed
US-5391807-A Methods of preparing fluorobenzene derivatives and related compounds SAGAMI CHEMICAL RESEARCH CENTER (JP) 1995-02-21 US disclosed
EP-0626370-A1 Process for producing aromatic isothiocyanate derivatives SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1994-11-30 EP disclosed
US-5344953-A Fluorobenzene derivatives SAGAMI CHEMICAL RESEARCH CENTER (JP) 1994-09-06 US disclosed
US-5281742-A Bis(fluorophenyl) carbonate derivatives SAGAMI CHEMICAL RESEARCH CENTER (JP) 1994-01-25 US disclosed
EP-0496347-A2 Methods of preparing fluorobenzene derivatives and related compounds SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-07-29 EP disclosed
US-5068365-A Herbicides TOSOH CORPORATION (JP) 1991-11-26 US disclosed
EP-0326764-A2 Hexahydrophthalic anilide derivatives and herbicide compositions containing the same Tosoh Corporation (JP) 1989-08-09 EP disclosed