Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27523012 | 0.81 | MEN1 (0.36) | LMNAHSP90AA1HSP90AB1TSHRKMT2A | |
| SCHEMBL7686746 | 0.81 | LMNA (0.43) | LMNAHSP90AA1HSP90AB1TSHRALOX15 | |
| SCHEMBL16797470 | 0.77 | KDM4E (0.42) | LMNAHSP90AA1HSP90AB1TSHRALOX15 | |
| SCHEMBL7686928 | 0.74 | MAP1LC3B (0.50) | LMNATSHRKMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7685341 | 0.71 | HPGD (0.34) | LMNAHSD17B10HPGD | |
| SCHEMBL7685368 | 0.69 | LMNA (0.58) | LMNAHSP90AA1HSP90AB1TSHRALOX15 | |
| SCHEMBL7685234 | 0.69 | ALOX15 (0.56) | LMNAHSP90AA1HSP90AB1TSHRALOX15 | |
| SCHEMBL7687667 | 0.68 | CSNK2A2 (0.44) | LMNAHSP90AA1HSP90AB1TSHRALOX15 | |
| SCHEMBL7685559 | 0.67 | HSP90AA1 (0.61) | LMNAHSP90AA1HSP90AB1TSHRALOX15 | |
| SCHEMBL14959525 | 0.67 | BRD4 (0.67) | TSHRKMT2AMEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350749-B1 | SODIUM CHANNEL MODULATORS, ANTIARRHYTHMIA AND HYPOTENSIVE AGENTS; CARDIOVASCULAR DISORDERS, ANGINA PECTORIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-02-26 | — | — | US | disclosed |
| EP-1057812-A1 | AMINOGUANIDINE HYDRAZONE DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND DRUGS THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2000-12-06 | — | — | EP | disclosed |