SCHEMBL7689542

SCHEMBL7689542

Cn1[nH]c2ccccc21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19937486 0.86 PSMB8 (0.48)
SCHEMBL14619854 0.73 ALDH1A1 (0.46)
SCHEMBL15934407 0.68
SCHEMBL23428744 0.68 ALOX5 (0.33)
SCHEMBL29845563 0.67 KDM4E (0.64)
SCHEMBL30336436 0.67 ALOX5 (1.00)
SCHEMBL2270654 0.67 KDM4E (0.64)
SCHEMBL21912895 0.65 RXFP1 (0.33)
SCHEMBL14374138 0.64 GPR3 (0.53)
SCHEMBL4636094 0.63 KDM4E (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023139133-A1 SHAPED ARTICLE COMPRISING A POLY(ARYL ETHER SULFONE) (PAES) POLYMER AND METHOD OF MAKING USING MELT PROCESSING SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2023-07-27 WO disclosed
WO-2022119864-A1 COMPOUNDS FOR THE TREATMENT OF SARS PURDUE RESEARCH FOUNDATION (US) 2022-06-09 WO disclosed
EP-3252052-B1 PHENANTHROLINE DERIVATIVE, ELECTRONIC DEVICE CONTAINING SAME, LIGHT EMITTING ELEMENT, AND PHOTOELECTRIC CONVERSION ELEMENT TORAY INDUSTRIES (JP) 2021-05-19 EP disclosed
EP-1699455-B1 HETEROCYCLIC ASPARTYL PROTEASE INHIBITORS MERCK SHARP & DOHME (US) 2013-05-08 EP disclosed
WO-2011163355-A1 FUSED HETEROCYCLIC COMPOUNDS AS PHOSPHODIESTERASES (PDES) INHIBITORS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2011-12-29 WO disclosed
WO-2007147217-A1 METHOD OF TREATMENT OF GLIOMA BRAIN TUMOUR PRANA BIOTECHNOLOGY LIMITED (AU) 2007-12-27 WO disclosed
WO-2007084390-A2 HISTONE DEACETYLASE INHIBITORS TAKEDA SAN DIEGO, INC. (US) 2007-07-26 WO disclosed