Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 5/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222284 | 1.00 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9ATDP1PDE10A | |
| Hydrogen Sulfide SCHEMBL28270010 | 0.98 | SMN1; SMN2 (0.52) | SMN1; SMN2NPC1RAB9ATDP1PDE10A | |
| Biphenyl SCHEMBL28350717 | 0.91 | NPC1 (0.52) | SMN1; SMN2NPC1RAB9ATDP1PDE10A | |
| SCHEMBL16151415 | 0.88 | SMN1; SMN2 (0.44) | SMN1; SMN2NPC1RAB9ATDP1PDE10A | |
| Sulfamide SCHEMBL28719576 | 0.88 | HTT (0.50) | SMN1; SMN2NPC1RAB9ATDP1PDE10A | |
| SCHEMBL6517140 | 0.88 | NPC1 (0.44) | SMN1; SMN2NPC1RAB9ATDP1PDE10A | |
| SCHEMBL28130845 | 0.88 | SMN1; SMN2 (0.44) | SMN1; SMN2NPC1RAB9ATDP1PDE10A | |
| SCHEMBL7689829 | 0.79 | ALDH1A1 (0.61) | SMN1; SMN2NPC1RAB9ATDP1ALDH1A1 | |
| SCHEMBL30754258 | 0.76 | TDP1 (0.48) | SMN1; SMN2NPC1RAB9ATDP1PDE10A | |
| SCHEMBL28156588 | 0.76 | ALDH1A1 (0.47) | SMN1; SMN2NPC1RAB9AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12410174-B1 | Small molecular inhibitors of sting signaling compositions and methods of use | TYERELL IMMUNOTHERAPEUTICS INC (US) | 2025-09-09 | — | — | US | disclosed |
| US-11897888-B1 | Small molecular inhibitors of sting signaling compositions and methods of use | STINGINN LLC (US) | 2024-02-13 | — | — | US | disclosed |
| CN-112533911-B | Compound and organic light emitting device comprising the same | 株式会社LG化学 | 2023-12-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12410174-B1 | Small molecular inhibitors of sting signaling compositions and methods of use | STING1, IRF3, MAVS | SMN1; SMN2 4511/4885NPC1 2753/4885RAB9A 2205/4885 |
| US-11897888-B1 | Small molecular inhibitors of sting signaling compositions and methods of use | STING1, IRF3, MAVS | SMN1; SMN2 4511/4885NPC1 2753/4885RAB9A 2205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.