SCHEMBL7689995

SCHEMBL7689995

CCc1nc(C)cn1[Si](C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.36
LMNA P02545 4/20 0.36
HTT P42858 4/20 0.36
TSHR P16473 3/20 0.36
MAPT P10636 2/20 0.36
CYP19A1 P11511 1/20 0.36
ALDH1A1 P00352 2/20 0.34
MAPK1 P28482 1/20 0.33
PDE2A O00408 1/20 0.33
PDE1A P54750 1/20 0.33
PDE1B Q01064 1/20 0.33
PDE3B Q13370 1/20 0.33
PDE1C Q14123 1/20 0.33
PDE3A Q14432 1/20 0.33
GAA P10253 1/20 0.33
KMT2A Q03164 1/20 0.33
GPR55 Q9Y2T6 1/20 0.31
PDE4A P27815 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28817475 0.75 LMNA (0.41) SMN1; SMN2LMNAHTTTSHRMAPT
SCHEMBL2512278 0.73
SCHEMBL27624956 0.71
SCHEMBL6855316 0.71 CYP19A1 (0.47) SMN1; SMN2LMNAHTTTSHRMAPT
SCHEMBL27846602 0.71
SCHEMBL27306894 0.71
SCHEMBL27353368 0.71
Ethane SCHEMBL28231212 0.70 LMNA (0.36) SMN1; SMN2LMNAHTTTSHRMAPT
SCHEMBL28037377 0.70 LMNA (0.38) SMN1; SMN2LMNAHTTTSHRMAPT
SCHEMBL23994635 0.68 CYP19A1 (0.39) SMN1; SMN2LMNAHTTTSHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240203727-A1 METHOD OF DEPOSITING SILICON-BASED MATERIAL AND PRECURSORS FOR THE SAME ASM IP HOLDING B.V. (NL) 2024-06-20 US disclosed
CN-118207515-A Method for depositing silicon-based materials and precursors thereof ASM IP私人控股有限公司 2024-06-18 CN disclosed
US-6335456-B1 REACTING AN AMIDE WITH SILYLATION AGENT; DISTILLATION ATOFINA (FR) 2002-01-01 US disclosed
US-20010056200-A1 Semi-continuous process for preparing bis-silyl carboxamides ATOFINA (FR) 2001-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010056200-A1 Semi-continuous process for preparing bis-silyl carboxamides ACMSD, BRD4, BICRA SMN1; SMN2 1131/4885LMNA 265/4885HTT 4222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.