Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 19/20 | 0.65 |
| ▸ | MMP2 | P08253 | 12/20 | 0.65 |
| ▸ | MMP1 | P03956 | 10/20 | 0.65 |
| ▸ | MMP3 | P08254 | 2/20 | 0.55 |
| ▸ | MMP9 | P14780 | 2/20 | 0.55 |
| ▸ | MMP7 | P09237 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MMP14 | P50281 | 1/20 | 0.52 |
| ▸ | MMP16 | P51512 | 1/20 | 0.52 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683904 | 1.00 | MMP13 (0.65) | MMP13MMP2MMP1MMP3MMP9 | |
| SCHEMBL7690204 | 1.00 | MMP13 (0.65) | MMP13MMP2MMP1MMP3MMP9 | |
| Hydrochloric Acid SCHEMBL7688004 | 0.86 | MMP13 (0.65) | MMP13MMP2MMP1MMP3MMP9 | |
| Hydrochloric Acid SCHEMBL7688009 | 0.86 | MMP13 (0.65) | MMP13MMP2MMP1MMP3MMP9 | |
| SCHEMBL7683909 | 0.84 | MMP13 (0.46) | MMP13MMP2MMP1MMP3MMP9 | |
| SCHEMBL7683898 | 0.84 | MMP13 (0.46) | MMP13MMP2MMP1MMP3MMP9 | |
| SCHEMBL6769491 | 0.79 | MMP13 (0.77) | MMP13MMP2MMP1 | |
| SCHEMBL6767563 | 0.79 | MMP13 (0.77) | MMP13MMP2MMP1 | |
| SCHEMBL6767568 | 0.79 | MMP13 (0.77) | MMP13MMP2MMP1 | |
| SCHEMBL6764610 | 0.78 | MMP13 (0.70) | MMP13MMP2MMP1MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476027-B1 | N-hydroxy 4-sulfonyl butanamide compounds | MONSANTO COMPANY | 2002-11-05 | — | — | US | disclosed |