Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 14/20 | 0.46 |
| ▸ | MMP2 | P08253 | 8/20 | 0.46 |
| ▸ | MMP1 | P03956 | 6/20 | 0.46 |
| ▸ | CASP1 | P29466 | 3/20 | 0.44 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | MMP7 | P09237 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP14 | P50281 | 1/20 | 0.41 |
| ▸ | MMP16 | P51512 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683898 | 1.00 | MMP13 (0.46) | MMP13MMP2MMP1CASP1MMP9 | |
| SCHEMBL7690204 | 0.84 | MMP13 (0.65) | MMP13MMP2MMP1MMP9MMP3 | |
| SCHEMBL7683904 | 0.84 | MMP13 (0.65) | MMP13MMP2MMP1MMP9MMP3 | |
| SCHEMBL7690202 | 0.84 | MMP13 (0.65) | MMP13MMP2MMP1MMP9MMP3 | |
| SCHEMBL18184670 | 0.71 | RIPK1 (0.47) | CASP1POLBLMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL7688009 | 0.71 | MMP13 (0.65) | MMP13MMP2MMP1MMP9MMP3 | |
| Hydrochloric Acid SCHEMBL7688004 | 0.71 | MMP13 (0.65) | MMP13MMP2MMP1MMP9MMP3 | |
| SCHEMBL12994829 | 0.68 | CASP1 (0.60) | CASP1POLB | |
| SCHEMBL20998613 | 0.67 | CASP1 (0.58) | MMP13MMP2MMP1CASP1MMP9 | |
| SCHEMBL20364686 | 0.67 | CASP1 (0.48) | CASP1POLBLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476027-B1 | N-hydroxy 4-sulfonyl butanamide compounds | MONSANTO COMPANY | 2002-11-05 | — | — | US | disclosed |