Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 16/20 | 0.70 |
| ▸ | MMP1 | P03956 | 6/20 | 0.65 |
| ▸ | MMP2 | P08253 | 9/20 | 0.60 |
| ▸ | MMP9 | P14780 | 3/20 | 0.60 |
| ▸ | MMP3 | P08254 | 1/20 | 0.54 |
| ▸ | MMP7 | P09237 | 1/20 | 0.54 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.52 |
| ▸ | MMP14 | P50281 | 1/20 | 0.52 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.52 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.52 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6764875 | 1.00 | MMP13 (0.70) | MMP13MMP1MMP2MMP9MMP3 | |
| SCHEMBL6764872 | 1.00 | MMP13 (0.70) | MMP13MMP1MMP2MMP9MMP3 | |
| SCHEMBL4700302 | 0.88 | MMP13 (0.55) | MMP13MMP1MMP2MMP9ADAM17 | |
| SCHEMBL7684276 | 0.86 | MMP1 (0.64) | MMP13MMP1MMP2MMP9MMP3 | |
| Hydrochloric Acid SCHEMBL7301531 | 0.84 | MMP13 (0.67) | MMP13MMP1MMP2MMP9MMP3 | |
| Hydrochloric Acid SCHEMBL7301537 | 0.84 | MMP13 (0.67) | MMP13MMP1MMP2MMP9MMP3 | |
| SCHEMBL8441721 | 0.83 | MMP1 (0.57) | MMP13MMP1MMP2MMP9MMP7 | |
| SCHEMBL6764587 | 0.83 | MMP1 (0.57) | MMP13MMP1MMP2MMP9MMP7 | |
| SCHEMBL7182155 | 0.82 | MMP13 (1.00) | MMP13MMP1MMP2MMP9MMP3 | |
| SCHEMBL7301867 | 0.82 | MMP13 (0.80) | MMP13MMP1MMP2MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716844-B2 | ENZYME INHIBITORS; ANTIINFLAMMATORY AGENTS, ANTIARTHRITIC AGENTS | PHARMACIA CORPORATION | 2004-04-06 | — | — | US | disclosed |
| EP-0984959-B1 | AROMATIC SULFONYL ALPHA-HYDROXY HYDROXAMIC ACID COMPOUNDS | PHARMACIA CORP (US) | 2003-09-24 | — | — | EP | disclosed |
| US-20020173508-A1 | Aromatic sulfonyl alpha-hydroxy hydroxamic acid compounds | PHARMACIA CORPORATION | 2002-11-21 | — | — | US | disclosed |
| US-6362183-B1 | PROTEASE INHIBITORS; RHEUMATIC DISEASES; ANTITUMOR AGENTS | G. D. SEARLE & COMPANY | 2002-03-26 | — | — | US | disclosed |
| EP-0984959-A4 | AROMATIC SULFONYL ALPHA-HYDROXY HYDROXAMIC ACID COMPOUNDS | MONSANTO CO (US) | 2001-05-02 | — | — | EP | disclosed |
| EP-0984959-A1 | AROMATIC SULFONYL ALPHA-HYDROXY HYDROXAMIC ACID COMPOUNDS | MONSANTO COMPANY (US) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998039326-A1 | AROMATIC SULFONYL ALPHA-HYDROXY HYDROXAMIC ACID COMPOUNDS | MONSANTO COMPANY (US) | 1998-09-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173508-A1 | Aromatic sulfonyl alpha-hydroxy hydroxamic acid compounds | MMP1, MMP2, MMP3 | MMP13 9/4885MMP1 1/4885MMP2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.