Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14692733 | 0.85 | GABRA1 (0.43) | GABRA1GABRB2ALDH1A1KDM4EMAPT | |
| SCHEMBL491175 | 0.82 | GABRA1 (0.46) | GABRA1GABRB2ALDH1A1KDM4EMAPT | |
| SCHEMBL17666848 | 0.80 | GABRA1 (0.47) | GABRA1GABRB2ALDH1A1KDM4EMAPT | |
| SCHEMBL8048832 | 0.79 | LIPG (0.41) | PRCPLIPG | |
| SCHEMBL28428231 | 0.79 | CEL (0.34) | KMT2AABCB1LIPG | |
| SCHEMBL27919603 | 0.79 | GABRA1 (0.39) | GABRA1GABRB2ALDH1A1KDM4EMAPT | |
| SCHEMBL27927530 | 0.78 | ABCB1 (0.44) | GABRA1GABRB2ALDH1A1KDM4EMAPT | |
| SCHEMBL27760348 | 0.78 | GABRA1 (0.38) | GABRA1GABRB2ALDH1A1KDM4EMAPT | |
| SCHEMBL27631593 | 0.78 | GABRA1 (0.38) | GABRA1GABRB2ALDH1A1KDM4EMAPT | |
| SCHEMBL9784205 | 0.77 | GABRA1 (0.40) | GABRA1GABRB2ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6388146-B1 | AROMATIC UNSATURATED NOMONER | SHARP KABUSHIKI KAISHA (JP) | 2002-05-14 | — | — | US | disclosed |