Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 5/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.49 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695406 | 0.89 | PDGFRB (0.54) | PDGFRBPDGFRACXCR2MEN1KMT2A | |
| SCHEMBL7696819 | 0.79 | PDGFRB (0.68) | PDGFRBPDGFRAMEN1KMT2APOLB | |
| SCHEMBL7695428 | 0.76 | MAPKAPK2 (0.44) | PDGFRBPDGFRACXCR2MEN1KMT2A | |
| SCHEMBL7697715 | 0.73 | PDGFRB (0.52) | PDGFRBPDGFRAMEN1KMT2ANPC1 | |
| SCHEMBL7697609 | 0.73 | MAPK10 (0.50) | PDGFRBPDGFRAMEN1KMT2AGAA | |
| SCHEMBL7695581 | 0.73 | PDGFRB (0.59) | PDGFRBPDGFRAMEN1KMT2AGAA | |
| SCHEMBL18796175 | 0.72 | PDGFRB (0.50) | PDGFRBPDGFRAMEN1KMT2AGAA | |
| SCHEMBL7699339 | 0.72 | PDGFRB (0.46) | PDGFRBPDGFRALMNAMAPK1 | |
| SCHEMBL7690435 | 0.72 | PDGFRB (0.59) | PDGFRBPDGFRAMEN1KMT2AGAA | |
| SCHEMBL7696400 | 0.71 | PDGFRB (0.76) | PDGFRBPDGFRAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |