Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3909568 | 0.82 | EGFR (0.57) | MAPK10PDGFRBPDGFRANPC1RAB9A | |
| SCHEMBL7696400 | 0.77 | PDGFRB (0.76) | PDGFRBPDGFRANPC1RAB9AALDH1A1 | |
| SCHEMBL7697848 | 0.76 | PDGFRB (0.56) | PDGFRBPDGFRANPC1RAB9AALDH1A1 | |
| SCHEMBL7694730 | 0.76 | PDGFRB (0.59) | MAPK10PDGFRBPDGFRANPC1RAB9A | |
| SCHEMBL7699339 | 0.75 | PDGFRB (0.46) | PDGFRBPDGFRA | |
| SCHEMBL31620733 | 0.73 | NPC1 (0.71) | MAPK10NPC1RAB9AALDH1A1GAA | |
| SCHEMBL7695428 | 0.73 | MAPKAPK2 (0.44) | PDGFRBPDGFRAGAAKMT2AMAPT | |
| SCHEMBL7690376 | 0.73 | PDGFRB (0.49) | PDGFRBPDGFRANPC1RAB9AGAA | |
| SCHEMBL7696743 | 0.72 | PDGFRB (0.59) | MAPK10PDGFRBPDGFRANPC1RAB9A | |
| SCHEMBL7695393 | 0.72 | PDGFRB (0.59) | MAPK10PDGFRBPDGFRANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |