Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 5/20 | 0.59 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | TTK | P33981 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7692274 | 0.77 | PDGFRB (0.71) | PDGFRBPDGFRAMAPTMAPK1 | |
| SCHEMBL4641001 | 0.75 | MAPT (0.58) | PDGFRBPDGFRAMAPTKDM4EALDH1A1 | |
| SCHEMBL1401415 | 0.74 | PDGFRB (1.00) | PDGFRBPDGFRAMAPTKDM4EALDH1A1 | |
| SCHEMBL3909786 | 0.73 | PDGFRB (1.00) | PDGFRBPDGFRAMAPTALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL3884102 | 0.73 | PDGFRB (0.97) | PDGFRBPDGFRAMAPTKDM4EALDH1A1 | |
| SCHEMBL7690376 | 0.72 | PDGFRB (0.49) | PDGFRBPDGFRAMAPTGAAMEN1 | |
| SCHEMBL7697609 | 0.72 | MAPK10 (0.50) | PDGFRBPDGFRAMAPTKDM4EALDH1A1 | |
| SCHEMBL7699339 | 0.71 | PDGFRB (0.46) | PDGFRBPDGFRALMNAMAPK1 | |
| SCHEMBL16332893 | 0.71 | GABRG2 (0.53) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7699357 | 0.71 | KMT2A (0.62) | MAPTKDM4EGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |