Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 6/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 6/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.41 |
| ▸ | SRC | P12931 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | BCR | P11274 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106618 | 0.88 | PDGFRB (0.53) | PDGFRBPDGFRAMAPK1THRBPIK3CA | |
| SCHEMBL7696264 | 0.87 | MAPT (0.41) | PDGFRBPDGFRAMAPK1THRBSRC | |
| SCHEMBL7695428 | 0.83 | MAPKAPK2 (0.44) | PDGFRBPDGFRA | |
| SCHEMBL7695393 | 0.81 | PDGFRB (0.59) | PDGFRBPDGFRAPIK3CA | |
| SCHEMBL7699322 | 0.78 | PDGFRB (0.71) | PDGFRBPDGFRA | |
| SCHEMBL7694733 | 0.77 | PDGFRB (0.41) | PDGFRBPDGFRA | |
| SCHEMBL7694543 | 0.75 | PDGFRB (0.52) | PDGFRBPDGFRAPIK3CA | |
| SCHEMBL7697609 | 0.75 | MAPK10 (0.50) | PDGFRBPDGFRA | |
| SCHEMBL18796175 | 0.74 | PDGFRB (0.50) | PDGFRBPDGFRATHRB | |
| SCHEMBL18796274 | 0.74 | PDGFRB (0.50) | PDGFRBPDGFRAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002094796-A2 | BENZO[G]QUINOXALINE DERIVATIVES AS EFFECTIVE COMPOUNDS AGAINST INFECTIOUS DISEASES | AXXIMA PHARMACEUTICALS AG (DE) | 2002-11-28 | — | — | WO | disclosed |