Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.67 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.48 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694783 | 0.84 | ALDH1A1 (0.72) | ALDH1A1CYP2C9CYP2C19MAPTGAA | |
| SCHEMBL7815320 | 0.81 | ALDH1A1 (0.68) | ALDH1A1CYP2C9CYP2C19FFAR3MAPT | |
| SCHEMBL13561158 | 0.81 | ADORA2B (0.74) | ALDH1A1CYP2C9CYP2C19ADORA2BMAPT | |
| SCHEMBL10280173 | 0.79 | ALDH1A1 (0.65) | ALDH1A1CYP2C9CYP2C19MAPTGAA | |
| SCHEMBL10112932 | 0.79 | ALDH1A1 (0.65) | ALDH1A1CYP2C9CYP2C19MAPTGAA | |
| SCHEMBL10112940 | 0.79 | ALDH1A1 (0.71) | ALDH1A1CYP2C9CYP2C19MAPTGAA | |
| SCHEMBL7692850 | 0.78 | ALDH1A1 (0.85) | ALDH1A1CYP2C9CYP2C19ADORA2BMAPT | |
| SCHEMBL7691449 | 0.76 | ADORA2B (1.00) | ALDH1A1ADORA2BKMT2APOLBKDM4E | |
| SCHEMBL7692642 | 0.75 | ALDH1A1 (0.78) | ALDH1A1CYP2C9CYP2C19MAPTGAA | |
| SCHEMBL7696439 | 0.75 | ALDH1A1 (0.60) | ALDH1A1CYP2C9CYP2C19MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002066443-A2 | 2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-08-29 | — | — | WO | claimed |
| WO-2002066443-A2 | 2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-08-29 | — | — | WO | disclosed |