Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | FFAR3 | O14843 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.63 |
| ▸ | BACE1 | P56817 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690395 | 0.81 | ALDH1A1 (1.00) | ALDH1A1CYP2C9CYP2C19FFAR3KDM4E | |
| SCHEMBL27372710 | 0.81 | KDM4E (0.77) | ALDH1A1CYP2C9CYP2C19FFAR3KDM4E | |
| SCHEMBL7806771 | 0.80 | ALDH1A1 (0.54) | ALDH1A1CYP2C9CYP2C19FFAR3KDM4E | |
| SCHEMBL7820648 | 0.80 | ALDH1A1 (0.55) | ALDH1A1CYP2C9CYP2C19FFAR3KDM4E | |
| SCHEMBL7817108 | 0.78 | KDM4E (0.77) | ALDH1A1KDM4ENPSR1BACE1HPGD | |
| SCHEMBL14825058 | 0.78 | ALDH1A1 (0.80) | ALDH1A1KDM4ENPSR1HPGDMAPT | |
| SCHEMBL10500289 | 0.77 | KDM4E (0.85) | ALDH1A1KDM4ENPSR1BACE1HPGD | |
| SCHEMBL7821246 | 0.76 | RAB9A (0.51) | ALDH1A1CYP2C9CYP2C19FFAR3KDM4E | |
| SCHEMBL7275684 | 0.76 | KDM4E (0.77) | ALDH1A1KDM4ENPSR1BACE1HPGD | |
| SCHEMBL7817530 | 0.75 | ALDH1A1 (0.52) | ALDH1A1CYP2C9CYP2C19FFAR3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265127-B1 | 1, 4-dihydrophyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY | 2001-07-24 | — | — | US | disclosed |
| EP-1109070-A2 | 1,4-Dihydropyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY (US) | 2001-06-20 | — | — | EP | disclosed |