Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582698 | 0.73 | RAB9A (0.42) | RAB9ANPC1MAOBMAPTSMN1; SMN2 | |
| SCHEMBL6623681 | 0.67 | RAB9A (0.47) | RAB9ANPC1MAOBMAPTSMN1; SMN2 | |
| SCHEMBL6629853 | 0.67 | HTT (0.50) | RAB9ANPC1MAOBMAPTSMN1; SMN2 | |
| SCHEMBL7007073 | 0.63 | PLA2G7 (0.49) | RAB9ANPC1MAOBMAPTSMN1; SMN2 | |
| SCHEMBL3715462 | 0.63 | HPGD (0.45) | RAB9ANPC1MAOBMAPTSMN1; SMN2 | |
| SCHEMBL28234324 | 0.62 | MEN1 (0.34) | RAB9ANPC1MEN1KMT2APOLB | |
| SCHEMBL88855 | 0.61 | ALDH1A1 (0.33) | TSHR | |
| SCHEMBL9744557 | 0.61 | ALDH1A1 (0.43) | RAB9ANPC1MAOBMAPTSMN1; SMN2 | |
| SCHEMBL14577156 | 0.61 | CCR1 (0.44) | RAB9ANPC1MAOBMAPTSMN1; SMN2 | |
| SCHEMBL13752162 | 0.61 | RAB9A (0.70) | RAB9ANPC1MAPTSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432988-B1 | RHEUMATIC DISEASES, (OSTEO)ARTHRITIS, CACHEXIA, INFLAMMATORY BOWEL DISEASE, TOXIC SHOCK SYNDROME, SEPSIS, CROHN*S DISEASE, PSORIASIS AND GOUT TREATMENT | MERCKLE GMBH (DE) | 2002-08-13 | — | — | US | disclosed |