Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.80 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 1/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.80 |
| ▸ | DHFR | P00374 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7691806 | 0.89 | ALDH1A1 (1.00) | ALDH1A1CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL7690545 | 0.77 | ALDH1A1 (1.00) | ALDH1A1CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL7356693 | 0.77 | DHFR (0.74) | ALDH1A1CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL7356688 | 0.77 | DHFR (0.74) | ALDH1A1CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL7694816 | 0.73 | ALDH1A1 (0.73) | ALDH1A1CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL7693286 | 0.73 | ALDH1A1 (0.73) | ALDH1A1CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL10113461 | 0.72 | DHFR (0.64) | ALDH1A1CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL10113034 | 0.72 | DHFR (0.76) | ALDH1A1CYP2C9CYP2C19MEN1KMT2A | |
| SCHEMBL10112919 | 0.72 | POLB (0.79) | ALDH1A1MEN1KMT2ADHFRSMN1; SMN2 | |
| SCHEMBL10113592 | 0.72 | MAPK1 (0.73) | ALDH1A1CYP2C9CYP2C19MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002066443-A2 | 2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-08-29 | — | — | WO | claimed |
| WO-2002066443-A2 | 2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-08-29 | — | — | WO | disclosed |