Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 6/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 6/20 | 0.46 |
| ▸ | PARP1 | P09874 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | NPY1R | P25929 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690696 | 0.79 | ALDH1A1 (0.47) | TNKSPARP2PARP1ALDH1A1NPY1R | |
| SCHEMBL7966182 | 0.78 | NPY1R (0.69) | NPY1R | |
| SCHEMBL7688416 | 0.75 | NPY1R (0.70) | NPY1R | |
| SCHEMBL8555618 | 0.75 | NPY1R (0.46) | NPY1RACHEBCHE | |
| SCHEMBL7688414 | 0.72 | NPY1R (0.51) | ALDH1A1NPY1RMAPTSMN1; SMN2GLA | |
| SCHEMBL11240335 | 0.70 | ALDH1A1 (0.66) | ALDH1A1ACHEHPGDKDM4EMAPT | |
| SCHEMBL8554479 | 0.69 | NPY1R (0.45) | ALDH1A1NPY1RMAPTLMNAKMT2A | |
| SCHEMBL7686457 | 0.68 | CHEK2 (0.45) | BCHE | |
| SCHEMBL6354128 | 0.67 | SLC6A4 (0.64) | ALDH1A1ACHEBCHEKMT2A | |
| SCHEMBL7682950 | 0.67 | NPY1R (0.75) | NPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020007071-A1 | Benzimidzolyl neuropeptide Y receptor antagonists | BRITTON THOMAS CHARLES (US) | 2002-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020007071-A1 | Benzimidzolyl neuropeptide Y receptor antagonists | NPY1R, NPY2R, NPY5R | TNKS 2132/4885PARP2 3621/4885PARP1 3539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.