Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 12/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551336 | 0.90 | GPR119 (0.47) | NPY1RDGAT2PRMT5FAAH | |
| SCHEMBL8554095 | 0.88 | NPY1R (0.58) | NPY1R | |
| SCHEMBL8556171 | 0.86 | NPY1R (0.45) | NPY1RDGAT2 | |
| SCHEMBL8555211 | 0.86 | GPR119 (0.45) | NPY1RDGAT2PRMT5FAAH | |
| SCHEMBL8552756 | 0.85 | GPR119 (0.45) | NPY1RDGAT2PRMT5FAAH | |
| SCHEMBL8557780 | 0.84 | GPR119 (0.44) | NPY1RDGAT2PRMT5FAAH | |
| SCHEMBL8552606 | 0.84 | DGAT2 (0.43) | NPY1RDGAT2HRH2HRH1LMNA | |
| SCHEMBL8554433 | 0.84 | NPY1R (0.47) | NPY1R | |
| SCHEMBL8554215 | 0.84 | NPY1R (0.49) | NPY1RDGAT2 | |
| SCHEMBL8551903 | 0.83 | NPY1R (0.54) | NPY1RFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |