Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25B | P30305 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CCR6 | P51684 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA7 | P43166 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 2/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | FGB | P02675 | 1/20 | 0.46 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | CDC25C | P30307 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27167364 | 0.84 | TSHR (0.50) | CDC25BTSHRCCR6KDM4EALDH1A1 | |
| SCHEMBL16112265 | 0.84 | TSHR (0.50) | CDC25BTSHRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL11431252 | 0.84 | KDM4E (0.60) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL24916110 | 0.82 | CA12 (0.47) | CDC25BTSHRCCR6CA12CA1 | |
| SCHEMBL7370092 | 0.82 | NUDT1 (0.52) | CDC25BTSHRCCR6KDM4EALDH1A1 | |
| SCHEMBL29923669 | 0.82 | CA12 (0.47) | CDC25BTSHRCCR6CA12CA1 | |
| SCHEMBL24916121 | 0.81 | ALDH1A1 (0.48) | CDC25BTSHRCCR6CA12CA1 | |
| SCHEMBL29923660 | 0.81 | ALDH1A1 (0.48) | CDC25BTSHRCCR6CA12CA1 | |
| SCHEMBL1462136 | 0.80 | TSHR (0.51) | CDC25BTSHRCCR6CA12CA1 | |
| SCHEMBL4465565 | 0.79 | CDC25B (0.69) | CDC25BTSHRCCR6CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |