Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | XPO1 | O14980 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690756 | 1.00 | DGAT1 (0.31) | DGAT1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL1879467 | 0.80 | GABRP (0.38) | DGAT1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL5390239 | 0.80 | GABRP (0.38) | DGAT1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL2543491 | 0.78 | HDAC3 (0.34) | DGAT1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL10445585 | 0.78 | HDAC3 (0.34) | DGAT1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL43764 | 0.78 | HCAR2 (0.45) | DGAT1HDAC1HDAC2HDAC6XPO1 | |
| SCHEMBL43004 | 0.78 | HCAR2 (0.45) | DGAT1HDAC1HDAC2HDAC6XPO1 | |
| SCHEMBL375029 | 0.78 | HCAR2 (0.45) | DGAT1HDAC1HDAC2HDAC6XPO1 | |
| SCHEMBL31188738 | 0.77 | GABRP (0.31) | DGAT1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL27638180 | 0.76 | HCAR2 (0.43) | DGAT1HDAC1HDAC2HDAC6XPO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342627-B1 | ESTER INTERCHANGE WITH ALCOHOL IN THE PRESENCE OF LANTHANOIDE METAL ALKOXIDE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-01-29 | — | — | US | disclosed |