Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 6/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | CNR1 | P21554 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7668133 | 0.87 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL7668231 | 0.87 | ALDH1A1 (0.63) | ALDH1A1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL7691765 | 0.82 | MAPK1 (0.59) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL7698867 | 0.80 | SMN1; SMN2 (0.51) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL7690567 | 0.78 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8023043 | 0.77 | LMNA (0.55) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL7663722 | 0.77 | ALDH1A1 (0.64) | ALDH1A1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL8019200 | 0.75 | LMNA (0.55) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL8019132 | 0.75 | SMN1; SMN2 (0.53) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL7697941 | 0.75 | NPC1 (0.58) | ALDH1A1MAPTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355633-B1 | CONTRACEPTIVES | AMERICAN HOME PRODUCTS CORPORATION | 2002-03-12 | — | — | US | disclosed |