Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665004 | 0.87 | LMNA (0.54) | LMNAKMT2AMAPK1ALDH1A1MEN1 | |
| SCHEMBL7665133 | 0.87 | LMNA (0.54) | LMNAKMT2AMAPK1ALDH1A1MEN1 | |
| SCHEMBL8023043 | 0.82 | LMNA (0.55) | LMNAKMT2AMAPK1ALDH1A1MEN1 | |
| SCHEMBL8019190 | 0.81 | RAB9A (0.66) | LMNAKMT2AMAPK1ALDH1A1MEN1 | |
| SCHEMBL8008535 | 0.81 | RAB9A (0.65) | LMNAKMT2AMAPK1ALDH1A1MEN1 | |
| SCHEMBL8023083 | 0.80 | RAB9A (0.56) | LMNAKMT2AMAPK1ALDH1A1MEN1 | |
| SCHEMBL8019132 | 0.80 | SMN1; SMN2 (0.53) | LMNAKMT2AMAPK1ALDH1A1MEN1 | |
| SCHEMBL8021345 | 0.79 | KMT2A (0.66) | LMNAKMT2AMAPK1ALDH1A1MEN1 | |
| SCHEMBL7666243 | 0.79 | L3MBTL1 (0.73) | LMNAKMT2AMAPK1ALDH1A1MEN1 | |
| SCHEMBL7691765 | 0.79 | MAPK1 (0.59) | LMNAKMT2AMAPK1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000058277-A1 | ARYL SULFONIC ACIDS AND DERIVATIVES AS FSH ANTAGONISTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-05 | — | — | WO | disclosed |