Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL447625 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KDM4EHSD17B10HPGDL3MBTL1 | |
| SCHEMBL31465688 | 0.83 | L3MBTL1 (0.55) | ALDH1A1KDM4EHSD17B10HPGDL3MBTL1 | |
| SCHEMBL2059537 | 0.82 | KDM4E (0.71) | ALDH1A1KDM4EHSD17B10HPGDL3MBTL1 | |
| SCHEMBL7877962 | 0.81 | TDP1 (0.51) | ALDH1A1KDM4EHSD17B10HPGDL3MBTL1 | |
| SCHEMBL8764787 | 0.79 | L3MBTL1 (0.55) | ALDH1A1KDM4EHSD17B10HPGDL3MBTL1 | |
| SCHEMBL25907019 | 0.78 | L3MBTL1 (0.46) | ALDH1A1KDM4EHSD17B10HPGDL3MBTL1 | |
| SCHEMBL982574 | 0.77 | L3MBTL1 (0.58) | ALDH1A1KDM4EHSD17B10HPGDL3MBTL1 | |
| SCHEMBL6363008 | 0.77 | TDP1 (0.46) | ALDH1A1KDM4EHSD17B10HPGDL3MBTL1 | |
| Acetic Acid SCHEMBL28743775 | 0.77 | KDM4E (0.70) | ALDH1A1KDM4EHSD17B10HPGDL3MBTL1 | |
| SCHEMBL6476583 | 0.77 | KMT2A (0.46) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002090360-A1 | COMPOUNDS USEFUL AS KINASE INHIBITORS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 2002-11-14 | — | — | WO | disclosed |