Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690998 | 0.78 | ALDH1A1 (0.52) | L3MBTL1SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL31465688 | 0.78 | L3MBTL1 (0.55) | L3MBTL1SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL8764787 | 0.74 | L3MBTL1 (0.55) | L3MBTL1SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL447625 | 0.74 | ALDH1A1 (0.49) | L3MBTL1SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL2059537 | 0.73 | KDM4E (0.71) | L3MBTL1SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL982574 | 0.73 | L3MBTL1 (0.58) | L3MBTL1SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL4812600 | 0.71 | L3MBTL1 (0.52) | L3MBTL1SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL10523979 | 0.71 | L3MBTL1 (0.52) | L3MBTL1SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL10959076 | 0.71 | L3MBTL1 (0.52) | L3MBTL1SMN1; SMN2ALDH1A1KDM4EHPGD | |
| SCHEMBL31465668 | 0.70 | L3MBTL1 (0.54) | L3MBTL1SMN1; SMN2ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11857650-B2 | Dental composition comprising a dental filler containing a structural filler and silanated glass flakes | DENTSPLY SIRONA INC. (US) | 2024-01-02 | — | — | US | disclosed |
| EP-3794075-B1 | MACROMONOMER BASED LIGHT-CURABLE DENTAL IMPRESSION MATERIAL | DENTSPLY SIRONA INC (US) | 2023-08-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11857650-B2 | Dental composition comprising a dental filler containing a structural filler and silanated glass flakes | DHX35, DHX30, FLNA | L3MBTL1 4592/4885SMN1; SMN2 4657/4885ALDH1A1 2605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.