Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | IL1RN | P18510 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 5/20 | 0.43 |
| ▸ | CTSK | P43235 | 4/20 | 0.43 |
| ▸ | CTSS | P25774 | 4/20 | 0.43 |
| ▸ | CTSL | P07711 | 4/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3739447 | 0.91 | MEN1 (0.45) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL3726974 | 0.84 | CYP3A4 (0.54) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL3727821 | 0.81 | MEN1 (0.45) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL2150881 | 0.80 | CTSB (0.58) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL22685692 | 0.80 | CTSB (0.58) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL2150884 | 0.80 | CTSB (0.58) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL3732282 | 0.80 | MEN1 (0.48) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL3729371 | 0.79 | CTSD (0.46) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL2221511 | 0.78 | CTSB (0.56) | CYP3A4CYP2D6CYP2C9CYP2C19RAB9A | |
| SCHEMBL3726931 | 0.75 | CTSL (0.48) | RAB9AMEN1KMT2ACTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6458772-B1 | Prodrugs | MEDIVIR AB (SE) | 2002-10-01 | — | — | US | disclosed |