SCHEMBL8853450

SCHEMBL8853450

C=C(C(=O)OOC(C)(C)OC(=O)OC(C)(C)OOC(=O)C(=C)C(C)(C)c1ccc(C(C)C)cc1)C(C)(C)c1ccc(C(C)C)cc1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
HIF1A Q16665 1/20 0.38
PTPN5 P54829 2/20 0.37
KIF11 P52732 1/20 0.32
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30
HTT P42858 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7692276 0.85 KMT2A (0.42) CYP2D6HIF1AALDH1A1MAPTMAPK1
SCHEMBL3384477 0.82 CYP2D6 (0.36) CYP2D6CYP2C9HIF1APTPN5KIF11
SCHEMBL4224938 0.82 CYP2D6 (0.38) CYP2D6CYP2C9HIF1APTPN5
SCHEMBL8762517 0.81 CYP2C9 (0.41) CYP2D6CYP2C9HIF1APTPN5KIF11
SCHEMBL8972312 0.78 CYP2D6 (0.40) CYP2D6CYP2C9HIF1APTPN5KIF11
SCHEMBL9847927 0.78 CYP2D6 (0.37) CYP2D6CYP2C9HIF1APTPN5
SCHEMBL8763275 0.77 CYP2D6 (0.36) CYP2D6CYP2C9HIF1APTPN5KIF11
SCHEMBL9851458 0.76 LMNA (0.39) CYP2D6CYP2C9HIF1APTPN5KIF11
SCHEMBL3385457 0.74 CYP2D6 (0.36) CYP2D6CYP2C9HIF1APTPN5KIF11
SCHEMBL9847983 0.72 EPHX1 (0.33) CYP2D6CYP2C9HIF1AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3284784-A1 METHACRYLIC RESIN COMPOSITION Kuraray Co., Ltd. (JP) 2018-02-21 EP disclosed
US-5674930-A MOLDING MATERIAL COMPRISING A BLEND OF A PROPYLENE BASED POLYMER AND A GRAFT ADDITION COPOLYMER; IMPACT STRENGTH, COATABILITY; BUMPER OF AUTOMOBILE NOF CORPORATION (JP) 1997-10-07 US disclosed
EP-0507561-B1 Thermoplastic resin compositions NOF CORP (JP) 1996-06-26 EP disclosed
EP-0423767-B1 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO LTD (JP) 1996-03-06 EP disclosed
EP-0338303-B1 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO LTD (JP) 1995-11-15 EP disclosed
US-5438098-A Blend of polyarylene sulfie;, polycarbonater and/or acrylonitrile-butadiene-styrene resin, and epoxy group containing defin graft polymer as compatibilizer NIPPON PETROCHEMICALS CO., LTD. (JP) 1995-08-01 US disclosed
US-5438108-A Melt-kneading a mixture of aromatic polycarbonate resin and vinylic copolymer containing active oxygen; optical distortion reduction MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1995-08-01 US disclosed
EP-0334296-B1 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO LTD (JP) 1995-06-07 EP disclosed
EP-0289933-B1 Graft polymerization precurser and method manufacturing the same NIPPON OILS & FATS CO LTD (JP) 1994-07-13 EP disclosed
US-5326817-A Blend of polyphenylene ether, polycarbonate or polyoxymethylene resins and multi-phase thermoplastic resins NIPPON PETROCHEMICALS CO. LTD. (JP) 1994-07-05 US disclosed
EP-0412572-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS CO., LTD. (JP) 1991-02-13 EP disclosed
US-4987165-A MULTIPHASE COMPATIBILIZER FOR BLEND OF POLYSULFONE AND ACRYLONITRILE-BUTADIENE-STYRENE TERPOLYMER NIPPON PETROCHEMICALS CO., LTD. (JP) 1991-01-22 US disclosed
US-4923956-A Containing free radical polymerizable organic peroxide NIPPON OIL AND FATS CO., LTD. (JP) 1990-05-08 US disclosed
US-4879347-A ETHYLENE POLYMER, VINYL MONOMER, RADICAL POLYMERIZABLE ORGANIC PEROXIDE, FREE RADICAL CATALYST, COPOLYMERIZATION NIPPON OIL AND FATS CO., LTD. (JP) 1989-11-07 US disclosed
US-4877841-A GRAFT POLYMER OF POLYETHYLENE, UNSATURATED MONOMER AND AN UNSATURATED PEROXYCARBONATE; SOLUBILIZERS FOR POLYMER BLENDS NIPPON OIL AND FATS CO., LTD. (JP) 1989-10-31 US disclosed
EP-0338544-A2 Thermoplastic resin composition and method for preparing the same NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1989-10-25 EP disclosed
US-4839432-A USING A UNSATURATED PEROXY FREE RADICAL CATALYSTS NIPPON OIL AND FATS CO., LTD. (JP) 1989-06-13 US disclosed
EP-0289933-A2 Graft polymerization precurser and method manufacturing the same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1988-11-09 EP disclosed
EP-0279430-A2 The method of manufacturing a grafted resin composition NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1988-08-24 EP disclosed
EP-0277608-A2 Graft polymerization preformer and method of manufacturing the same NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1988-08-10 EP disclosed