Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.39 |
| ▸ | SNCA | P37840 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7690172 | 0.81 | NOX1 (0.41) | NOX1SNCABCHEACHEMEN1 | |
| SCHEMBL7685864 | 0.81 | SNCA (0.59) | NOX1SNCAMEN1ALDH1A1MAPT | |
| SCHEMBL7692666 | 0.77 | NOX1 (0.39) | NOX1SNCABCHEACHEMEN1 | |
| SCHEMBL7689238 | 0.75 | NOX1 (0.40) | NOX1SNCABCHEACHEMEN1 | |
| SCHEMBL7673182 | 0.70 | NOX1 (0.62) | NOX1SNCABCHEACHEMEN1 | |
| SCHEMBL30697368 | 0.70 | NOX1 (0.62) | NOX1SNCABCHEACHEMEN1 | |
| SCHEMBL7688195 | 0.69 | NOX1 (0.49) | NOX1BCHEACHEMEN1ALDH1A1 | |
| SCHEMBL9671045 | 0.69 | NOX1 (0.51) | NOX1SNCABCHEACHEMEN1 | |
| Hydrochloric Acid SCHEMBL20495637 | 0.69 | NOX1 (0.60) | NOX1SNCABCHEACHEMEN1 | |
| Hydrochloric Acid SCHEMBL30448208 | 0.69 | NOX1 (0.60) | NOX1SNCABCHEACHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002539202-A | — | — | 2002-11-19 | — | — | JP | claimed |
| EP-1163233-A1 | FUSED 1,4-THIAZINE-2-CARBONITRILE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2001-12-19 | — | — | EP | claimed |
| WO-2000055147-A1 | FUSED 1,4-THIAZINE-2-CARBONITRILE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-09-21 | — | — | WO | claimed |
| EP-1163233-A1 | FUSED 1,4-THIAZINE-2-CARBONITRILE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2001-12-19 | — | — | EP | disclosed |
| WO-2000055147-A1 | FUSED 1,4-THIAZINE-2-CARBONITRILE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2000-09-21 | — | — | WO | disclosed |