Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 11/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | CYBB | P04839 | 1/20 | 0.43 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.43 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9671163 | 0.83 | NOX1 (0.61) | NOX1BCHEACHECYBBNOX3 | |
| SCHEMBL28117917 | 0.78 | NOX1 (0.76) | NOX1BCHEACHECYBBNOX3 | |
| SCHEMBL9759078 | 0.76 | NOX1 (0.55) | NOX1BCHEACHECYBBNOX3 | |
| SCHEMBL30697368 | 0.74 | NOX1 (0.62) | NOX1BCHEACHESNCAMAPT | |
| SCHEMBL7673182 | 0.74 | NOX1 (0.62) | NOX1BCHEACHESNCAMAPT | |
| SCHEMBL28110666 | 0.74 | NOX1 (0.58) | NOX1BCHEACHECYBBNOX3 | |
| Hydrochloric Acid SCHEMBL30448208 | 0.73 | NOX1 (0.60) | NOX1BCHEACHESNCAMAPT | |
| Hydrochloric Acid SCHEMBL20495637 | 0.73 | NOX1 (0.60) | NOX1BCHEACHESNCAMAPT | |
| SCHEMBL19744471 | 0.72 | NOX1 (0.57) | NOX1BCHEACHECYBBNOX3 | |
| SCHEMBL1855994 | 0.71 | NOX1 (0.65) | NOX1BCHEACHECYBBNOX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0163551-B1 | PHENOTHIAZINE COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-08-12 | — | — | EP | disclosed |
| US-4705854-A | ANTIALLERGENS, ANTIHISTAMINES | BURROUGHS WELLCOME CO. (US) | 1987-11-10 | — | — | US | disclosed |
| EP-0163551-A1 | Phenothiazine compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1985-12-04 | — | — | EP | disclosed |