Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.56 |
| ▸ | TUBB | P07437 | 6/20 | 0.56 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.56 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.56 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.56 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.56 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.56 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.56 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.56 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.56 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.56 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.56 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.56 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.56 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5391813 | 0.81 | RAF1 (0.62) | HPGDALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL11865449 | 0.81 | NPC1 (0.65) | ALDH1A1KDM4ETUBB4ATUBBTUBA3C | |
| SCHEMBL6791011 | 0.79 | LCK (0.56) | ALDH1A1KDM4EL3MBTL1TUBB4ATUBB | |
| SCHEMBL14097463 | 0.78 | CSNK1E (0.47) | ALDH1A1KDM4ENPC1RAB9ACYP1A2 | |
| SCHEMBL11801720 | 0.77 | SPHK2 (0.68) | ALDH1A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2671396 | 0.77 | KDM4E (0.49) | HPGDALDH1A1KDM4EL3MBTL1NPC1 | |
| SCHEMBL29511469 | 0.76 | TUBB4A (0.91) | HPGDALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL28753130 | 0.76 | TUBB4A (0.91) | HPGDALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL8632161 | 0.76 | MAPT (0.55) | ALDH1A1L3MBTL1NPC1RAB9AMAPK1 | |
| SCHEMBL11449015 | 0.76 | TUBB4A (0.49) | ALDH1A1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002016327-A1 | BENZIMIDAZOLES AND ANALOGUES AND THEIR USE AS NEUTROPHIL INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 2002-02-28 | — | — | WO | disclosed |