Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.41 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 4/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.31 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.31 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.31 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.31 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.31 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.31 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.31 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.31 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.31 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9741931 | 0.85 | ZDHHC20 (0.41) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL19253889 | 0.81 | ZDHHC20 (0.47) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL29407377 | 0.81 | TSHR (0.35) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL4434801 | 0.80 | ZDHHC20 (0.50) | ALDH1A1MAPK1ZDHHC20ZDHHC2THRA | |
| SCHEMBL2155070 | 0.79 | TSHR (0.41) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL3279249 | 0.79 | TSHR (0.43) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL27747237 | 0.79 | TSHR (0.37) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| Hydrochloric Acid SCHEMBL4601127 | 0.78 | ZDHHC20 (0.49) | ALDH1A1MAPK1ZDHHC20ZDHHC2THRA | |
| SCHEMBL24465165 | 0.76 | TSHR (0.33) | TSHRALDH1A1ZDHHC20ZDHHC2HPGD | |
| SCHEMBL27737214 | 0.76 | TSHR (0.41) | TSHRALDH1A1MAPK1TDP1ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101233148-A | Macrocyclic peptides as HCV NS3 protease inhibitors | MERCK & CO INC (US) | 2008-07-30 | — | — | CN | disclosed |
| WO-2002020487-A1 | SUBSTITUTED 1-ARYL-PYRIDIN-2-(THI)ONES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-14 | — | — | WO | disclosed |
| EP-0516305-B1 | Simultaneous use of water soluble polymers with ozone in cooling water systems | NALCO CHEMICAL CO (US) | 1996-10-16 | — | — | EP | disclosed |
| US-5171451-A | Homo- and copolymers of (meth)acrylic acid and their salts; calcium carbonate saturation ratio retained; antiscaling agents, corrosion resistance | NALCO CHEMICAL COMPANY (US) | 1992-12-15 | — | — | US | disclosed |
| EP-0516305-A1 | Simultaneous use of water soluble polymers with ozone in cooling water systems | NALCO CHEMICAL COMPANY (US) | 1992-12-02 | — | — | EP | disclosed |