Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.50 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4601127 | 0.98 | ZDHHC20 (0.49) | ZDHHC20ZDHHC2THRATHRBEPHX2 | |
| SCHEMBL19253889 | 0.94 | ZDHHC20 (0.47) | ZDHHC20ZDHHC2THRATHRBMEN1 | |
| SCHEMBL9741931 | 0.86 | ZDHHC20 (0.41) | ZDHHC20ZDHHC2THRATHRBALDH1A1 | |
| SCHEMBL7693137 | 0.80 | TSHR (0.42) | ZDHHC20ZDHHC2THRATHRBALDH1A1 | |
| SCHEMBL7326046 | 0.79 | ALDH1A1 (0.36) | ZDHHC20ZDHHC2EPHX2MEN1ALDH1A1 | |
| SCHEMBL8091952 | 0.78 | FAAH (0.43) | EPHX2PTPN1FAAH | |
| SCHEMBL3220018 | 0.76 | PTPN1 (0.43) | PTPN1FAAH | |
| SCHEMBL13113281 | 0.76 | FAAH (0.41) | PTPN1FAAH | |
| SCHEMBL8518454 | 0.76 | FAAH (0.50) | ZDHHC20ZDHHC2EPHX2ALDH1A1MAPT | |
| SCHEMBL1347954 | 0.75 | RELA (0.41) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117447505-A | Preparation method of beta-silicon-based amide-carboxylic acid medicine hybrid | 安阳师范学院 | 2024-01-26 | — | — | CN | claimed |
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | claimed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | claimed |
| CN-117447505-A | Preparation method of beta-silicon-based amide-carboxylic acid medicine hybrid | 安阳师范学院 | 2024-01-26 | — | — | CN | disclosed |
| CN-117447505-A | Preparation method of beta-silicon-based amide-carboxylic acid medicine hybrid | 安阳师范学院 | 2024-01-26 | — | — | CN | disclosed |
| EP-2735562-B2 | Estrogen receptor modulators and uses thereof | SERAGON PHARMACEUTICALS INC (US) | 2023-11-15 | — | — | EP | disclosed |
| CN-115583961-A | Synthetic method of alpha-quaternary carbon beta-silicon-based amide | 安阳师范学院 | 2023-01-10 | — | — | CN | disclosed |
| CN-115583961-A | Synthetic method of alpha-quaternary carbon beta-silicon-based amide | 安阳师范学院 | 2023-01-10 | — | — | CN | disclosed |
| CN-113527267-B | C2 symmetric duplex nitrogen heterocyclic ring fluorocarbon surfactant and preparation of aqueous phase micelle thereof | 山东盛安贝新能源有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-113527264-B | Method for synthesizing nitrogen-containing heterocyclic fluorocarbon surfactant by adopting photoreaction-click reaction and preparation of aqueous phase micelle thereof | 山东盛安贝新能源有限公司 | 2022-09-02 | — | — | CN | disclosed |
| CN-113527264-A | Method for synthesizing nitrogen-containing heterocyclic fluorocarbon surfactant by adopting photoreaction-click reaction and preparation of aqueous phase micelle thereof | 山东盛安贝新能源有限公司 | 2021-10-22 | — | — | CN | disclosed |
| CN-113527267-A | C2 symmetric duplex nitrogen heterocyclic ring fluorocarbon surfactant and preparation of aqueous phase micelle thereof | 山东盛安贝新能源有限公司 | 2021-10-22 | — | — | CN | disclosed |
| EP-2118066-A1 | FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA | Takeda Pharmaceutical Company Limited (JP) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008099794-A1 | FUSED RING COMPOUNDS AS PARTIAL AGONISTS OF PPAR-GAMMA | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-08-21 | — | — | WO | disclosed |
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |