Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | TEK | Q02763 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | IDE | P14735 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7688923 | 0.96 | MAPT (0.38) | METPPARGPPARAALDH1A1CYP2C9 | |
| SCHEMBL7693606 | 0.94 | F2 (0.37) | METPPARGPPARAALDH1A1CYP2C9 | |
| SCHEMBL7687505 | 0.91 | MET (0.38) | METPPARGPPARAALDH1A1CYP2C9 | |
| SCHEMBL7694588 | 0.91 | SPHK2 (0.38) | METALDH1A1CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL7698067 | 0.90 | MET (0.43) | METCYP2D6CYP3A4AURKAKDR | |
| SCHEMBL7698073 | 0.90 | MET (0.43) | METCYP2D6CYP3A4AURKAKDR | |
| SCHEMBL6478360 | 0.89 | MAPT (0.39) | METALDH1A1CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL7686458 | 0.89 | ALDH1A1 (0.35) | METALDH1A1CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL7692473 | 0.88 | MET (0.38) | METALDH1A1CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL7692428 | 0.88 | ADRB3 (0.37) | METALDH1A1CYP2C9CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |