Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 8/20 | 0.43 |
| ▸ | KDR | P35968 | 6/20 | 0.43 |
| ▸ | AURKA | O14965 | 5/20 | 0.43 |
| ▸ | TEK | Q02763 | 5/20 | 0.43 |
| ▸ | LCK | P06239 | 3/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | LYN | P07948 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | LOX | P28300 | 4/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698067 | 1.00 | MET (0.43) | METKDRAURKATEKLCK | |
| SCHEMBL7694588 | 0.94 | SPHK2 (0.38) | METKDRAURKATEKLCK | |
| SCHEMBL7687505 | 0.92 | MET (0.38) | METKDRAURKATEKLCK | |
| SCHEMBL7692473 | 0.91 | MET (0.38) | METKDRAURKATEKLCK | |
| SCHEMBL7693432 | 0.90 | MET (0.39) | METKDRAURKATEKLCK | |
| SCHEMBL7693347 | 0.90 | MET (0.35) | METKDRAURKATEKLCK | |
| SCHEMBL7688923 | 0.89 | MAPT (0.38) | METKDRFLT1CYP3A4CYP2D6 | |
| SCHEMBL7689561 | 0.89 | MET (0.40) | METCYP3A4CYP2D6LPAR1LPAR5 | |
| SCHEMBL7693606 | 0.89 | F2 (0.37) | METCYP2D6LMNANPC1LPAR1 | |
| SCHEMBL7686564 | 0.89 | LPAR1 (0.43) | METCYP2D6LPAR1LPAR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |