SCHEMBL769392

SCHEMBL769392

N#Cc1ccc(I)cc1C#N

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOB P27338 13/20 0.42
MAOA P21397 11/20 0.42
ALDH1A1 P00352 4/20 0.38
KDM4E B2RXH2 2/20 0.38
USP2 O75604 1/20 0.38
TRPV4 Q9HBA0 2/20 0.37
LMNA P02545 2/20 0.36
HTT P42858 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
THRB P10828 1/20 0.36
CYP19A1 P11511 1/20 0.35
HPGD P15428 1/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3979962 0.83 ALDH1A1 (0.61) MAOBMAOAALDH1A1KDM4EUSP2
SCHEMBL21687452 0.82 TRPV4 (0.35) MAOBMAOAALDH1A1KDM4EUSP2
SCHEMBL1914246 0.82 GRM4 (0.38) TRPV4
SCHEMBL301704 0.78 TRPV4 (0.43) TRPV4
SCHEMBL21222828 0.78 MAOB (0.37) MAOBMAOAALDH1A1KDM4EUSP2
SCHEMBL3336251 0.78 VCAM1 (0.48) MAOBMAOATRPV4MAPK1
SCHEMBL171635 0.78 TRPV4 (0.57) TRPV4
SCHEMBL3376010 0.78 TSHR (0.48) MAOBMAOAALDH1A1KDM4EUSP2
SCHEMBL875899 0.78 ERN1 (0.42) MAOBMAOACYP19A1
SCHEMBL445455 0.78 TRPV4 (0.57) MAOBMAOATRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119764554-A Composition for electrolyte, preparation method of electrolyte and lithium ion battery 国网湖南省电力有限公司 2025-04-04 CN claimed
CN-119330339-A Method for preparing porous carbon based on synchronous synthesis of nitrile resin/graphene nanosheets and porous carbon material 成都大学 2025-01-21 CN claimed
CN-111732839-B Phthalocyanine D-Pi-A type asymmetric disc-shaped dye and preparation method thereof 苏州优特创优新材料科技有限公司 2022-05-13 CN claimed
CN-111875794-A Novel preparation method of nitrile resin monomer 成都大学 2020-11-03 CN claimed
CN-111732839-A Phthalocyanine D-pi-A type asymmetric disc dye and preparation method thereof 南京优写智能科技有限公司 2020-10-02 CN claimed
US-10280147-B2 Solid-supported palladium (II) complex as a heterogeneous catalyst for cross coupling reactions and methods thereof KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2019-05-07 US claimed
US-20170275318-A1 SOLID-SUPPORTED PALLADIUM (II) COMPLEX AS A HETEROGENEOUS CATALYST FOR CROSS COUPLING REACTIONS AND METHODS THEREOF KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2017-09-28 US claimed
WO-2026101482-A1 MOLECULAR ORGANIC CRYSTAL-BASED LABELING SYSTEM T.C. ERCIYES UNIVERSITESI (TR) 2026-05-15 WO disclosed
CN-119764554-B Composition for electrolyte, preparation method of electrolyte and lithium ion battery 国网湖南省电力有限公司 2025-12-02 CN disclosed
CN-119764554-A Composition for electrolyte, preparation method of electrolyte and lithium ion battery 国网湖南省电力有限公司 2025-04-04 CN disclosed
CN-119764554-A Composition for electrolyte, preparation method of electrolyte and lithium ion battery 国网湖南省电力有限公司 2025-04-04 CN disclosed
CN-119330339-A Method for preparing porous carbon based on synchronous synthesis of nitrile resin/graphene nanosheets and porous carbon material 成都大学 2025-01-21 CN disclosed
EP-3885340-B1 ANDROGEN RECEPTOR MODULATING COMPOUNDS ORION CORP (FI) 2024-11-27 EP disclosed
EP-0971892-A1 NOVEL PYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM Astra Pharmaceuticals Limited (GB) 2000-01-19 EP disclosed
WO-1998042670-A1 NOVEL PYRIDINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM ASTRA PHARMACEUTICALS LTD. (GB) 1998-10-01 WO disclosed
US-4351776-A Preparation of iodophthalonitrile THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1982-09-28 US disclosed
US-4315093-A Fluorinated polyphthalocyanines THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1982-02-09 US disclosed
US-4315093-A Fluorinated polyphthalocyanines THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1982-02-09 US disclosed
US-4209458-A Fluorinated phthalonitriles THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1980-06-24 US disclosed
US-4209458-A Fluorinated phthalonitriles THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1980-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170275318-A1 SOLID-SUPPORTED PALLADIUM (II) COMPLEX AS A HETEROGENEOUS CATALYST FOR CROSS COUPLING REACTIONS AND METHODS THEREOF SIK1, SIK2, ULK2 MAOB 1500/4885MAOA 1176/4885ALDH1A1 1726/4885
US-10280147-B2 Solid-supported palladium (II) complex as a heterogeneous catalyst for cross coupling reactions and methods thereof SIK1, SIK2, ULK2 MAOB 1500/4885MAOA 1176/4885ALDH1A1 1726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.