Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694233 | 0.93 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1GAANPC1RAB9A | |
| SCHEMBL7693843 | 0.90 | TRPV1 (0.47) | SMN1; SMN2ALDH1A1GAANPC1RAB9A | |
| SCHEMBL7699798 | 0.87 | GAA (0.59) | SMN1; SMN2ALDH1A1GAANPC1RAB9A | |
| SCHEMBL7698238 | 0.82 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1GAAMAPTRXFP1 | |
| SCHEMBL7699977 | 0.81 | MAPT (0.49) | SMN1; SMN2ALDH1A1GAAMAPTRXFP1 | |
| SCHEMBL7699604 | 0.80 | MAPT (0.47) | SMN1; SMN2ALDH1A1GAANPC1RAB9A | |
| SCHEMBL7696428 | 0.79 | STAT3 (0.55) | SMN1; SMN2ALDH1A1GAANPC1RAB9A | |
| SCHEMBL7693822 | 0.79 | NR1H4 (0.48) | SMN1; SMN2ALDH1A1GAANPC1RAB9A | |
| SCHEMBL7699232 | 0.77 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1GAANPC1RAB9A | |
| SCHEMBL7695132 | 0.77 | MAPT (0.49) | SMN1; SMN2ALDH1A1GAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |