Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695765 | 0.93 | ALDH1A1 (0.50) | ALDH1A1NPSR1MEN1TSHRMAPK1 | |
| SCHEMBL7699977 | 0.91 | MAPT (0.49) | ALDH1A1NPSR1MEN1TSHRMAPK1 | |
| SCHEMBL7699503 | 0.88 | ALDH1A1 (0.56) | ALDH1A1NPSR1MEN1TSHRMAPK1 | |
| SCHEMBL7697100 | 0.85 | MAPT (0.47) | ALDH1A1MEN1MAPK1KMT2AHPGD | |
| SCHEMBL7695493 | 0.85 | NR1H4 (0.44) | ALDH1A1NPSR1MEN1TSHRMAPK1 | |
| SCHEMBL7694095 | 0.82 | SMN1; SMN2 (0.49) | ALDH1A1MEN1MAPK1KMT2AKDM4E | |
| SCHEMBL7696428 | 0.81 | STAT3 (0.55) | ALDH1A1MEN1TSHRKMT2AHPGD | |
| SCHEMBL7695519 | 0.80 | MAPT (0.61) | ALDH1A1NPSR1MEN1TSHRMAPK1 | |
| SCHEMBL7699812 | 0.79 | MEN1 (0.56) | ALDH1A1NPSR1MEN1TSHRMAPK1 | |
| SCHEMBL7698685 | 0.78 | DGAT1 (0.50) | ALDH1A1MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |