Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7701056 | 0.97 | MAPT (0.47) | ALDH1A1GAASMN1; SMN2MAPTRXFP1 | |
| SCHEMBL7701939 | 0.90 | HSP90AA1 (0.47) | ALDH1A1GAASMN1; SMN2MAPTRXFP1 | |
| SCHEMBL7699243 | 0.89 | TP53 (0.47) | ALDH1A1GAASMN1; SMN2MAPTKDM4E | |
| SCHEMBL7695157 | 0.87 | IKBKB (0.48) | ALDH1A1MAPTKDM4ETP53IKBKB | |
| SCHEMBL7698726 | 0.86 | LMNA (0.47) | MAPTIKBKBRAB9AMAPK1 | |
| SCHEMBL7704094 | 0.86 | MAPT (0.44) | ALDH1A1SMN1; SMN2MAPTKDM4ETP53 | |
| SCHEMBL7693804 | 0.85 | IKBKB (0.45) | ALDH1A1MAPTKDM4EDGAT1TP53 | |
| SCHEMBL7695326 | 0.84 | IKBKB (0.40) | ALDH1A1GAASMN1; SMN2MAPTRXFP1 | |
| SCHEMBL7693979 | 0.84 | IKBKB (0.42) | ALDH1A1MAPTRXFP1KDM4ESIRT1 | |
| SCHEMBL7697561 | 0.84 | POLB (0.54) | ALDH1A1GAASMN1; SMN2KDM4ESIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |