Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694273 | 0.79 | ROCK2 (0.43) | ROCK2ALDH1A1ROCK1MEN1KMT2A | |
| SCHEMBL5582742 | 0.78 | MCHR1 (0.57) | — | |
| SCHEMBL5582592 | 0.77 | ROCK2 (0.56) | ROCK2ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL5582721 | 0.75 | RAB9A (0.55) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL5582549 | 0.74 | ROCK2 (0.38) | MAPTROCK2ALDH1A1MEN1KMT2A | |
| SCHEMBL5582955 | 0.73 | MCHR1 (0.58) | ROCK2 | |
| SCHEMBL5582758 | 0.73 | USP2 (0.42) | MAPTROCK2ALDH1A1ROCK1ACHE | |
| SCHEMBL5582638 | 0.72 | CYP3A4 (0.53) | MAPTL3MBTL1LMNANPC1RAB9A | |
| SCHEMBL5583074 | 0.71 | RAB9A (0.53) | MAPTL3MBTL1ALDH1A1LMNAGAA | |
| SCHEMBL5582928 | 0.71 | CACNA2D1 (0.46) | MAPTALDH1A1LMNAGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218336-A2 | MELANIN CONCENTRATING HORMONE ANTAGONIST | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001021577-A2 | MELANIN CONCENTRATING HORMONE ANTAGONIST | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-03-29 | — | — | WO | disclosed |