Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2640855 | 0.98 | AR (0.33) | ARHPGDELANESMN1; SMN2 | |
| SCHEMBL1024623 | 0.96 | EPHX1 (0.33) | ARHPGDALDH1A1L3MBTL1KDM4E | |
| SCHEMBL4963186 | 0.82 | ACE (0.40) | LMNA | |
| SCHEMBL27718628 | 0.82 | ACE (0.40) | LMNA | |
| SCHEMBL10905425 | 0.79 | ACE (0.41) | LMNA | |
| SCHEMBL2860961 | 0.78 | ALDH1A1 (0.39) | HPGDALDH1A1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL16761709 | 0.78 | L3MBTL1 (0.37) | ALDH1A1L3MBTL1 | |
| SCHEMBL8175918 | 0.76 | HTT (0.33) | HPGDALDH1A1L3MBTL1KDM4ESMN1; SMN2 | |
| SCHEMBL28769295 | 0.76 | POLB (0.44) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11127735 | 0.72 | POLB (0.44) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028829-A2 | PEPTIDE DEFORMYLASE INHIBITORS | QUESTCOR PHARMACEUTICALS, INC. (US) | 2002-04-11 | — | — | WO | claimed |