Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698114 | 0.91 | MAPT (0.48) | HSD17B10MAPTPOLBUSP2TSHR | |
| SCHEMBL7699090 | 0.86 | MAPT (0.40) | HSD17B10MAPTPOLBUSP2TSHR | |
| SCHEMBL7695678 | 0.86 | CHRNB2 (0.49) | HSD17B10MAPTPOLBUSP2TSHR | |
| SCHEMBL7699604 | 0.86 | MAPT (0.47) | HSD17B10MAPTTSHRALDH1A1KMT2A | |
| SCHEMBL7699719 | 0.86 | MAPT (0.46) | HSD17B10MAPTTSHRHTTALDH1A1 | |
| SCHEMBL7695817 | 0.86 | MAOB (0.42) | HSD17B10MAPTPOLBUSP2TSHR | |
| SCHEMBL7695132 | 0.85 | MAPT (0.49) | MAPTTSHRALDH1A1KMT2AMEN1 | |
| SCHEMBL7694233 | 0.83 | SMN1; SMN2 (0.44) | HSD17B10MAPTPOLBUSP2ALDH1A1 | |
| SCHEMBL7699148 | 0.82 | MAPT (0.48) | MAPTALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL7695160 | 0.81 | MAPT (0.41) | HSD17B10MAPTUSP2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |