Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694375 | 0.91 | HSD17B10 (0.40) | MAPTTSHRHSD17B10HTTUSP2 | |
| SCHEMBL7699090 | 0.91 | MAPT (0.40) | MAPTTSHRHSD17B10HTTUSP2 | |
| SCHEMBL7695678 | 0.91 | CHRNB2 (0.49) | MAPTTSHRHSD17B10HTTUSP2 | |
| SCHEMBL7699604 | 0.90 | MAPT (0.47) | MAPTTSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL7699719 | 0.90 | MAPT (0.46) | MAPTTSHRHSD17B10HTTKDM4E | |
| SCHEMBL7695817 | 0.90 | MAOB (0.42) | MAPTTSHRHSD17B10HTTUSP2 | |
| SCHEMBL7695132 | 0.89 | MAPT (0.49) | MAPTTSHRKDM4EALDH1A1LMNA | |
| SCHEMBL7699148 | 0.87 | MAPT (0.48) | MAPTKDM4EALDH1A1LMNAMEN1 | |
| SCHEMBL7695160 | 0.85 | MAPT (0.41) | MAPTTSHRHSD17B10USP2KDM4E | |
| SCHEMBL7698104 | 0.84 | MAPT (0.51) | MAPTTSHRHSD17B10POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |