Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695132 | 0.95 | MAPT (0.49) | MAPTCYP3A4ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL7699604 | 0.94 | MAPT (0.47) | MAPTCYP3A4ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL7701479 | 0.89 | HSP90AA1 (0.54) | MAPTCYP3A4ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL7698114 | 0.87 | MAPT (0.48) | MAPTALDH1A1KMT2AMEN1RXFP1 | |
| SCHEMBL7702049 | 0.85 | DGAT1 (0.47) | MAPTCYP3A4ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL7699090 | 0.84 | MAPT (0.40) | MAPTCYP3A4ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL7698104 | 0.84 | MAPT (0.51) | MAPTALDH1A1KMT2AMEN1CYP1A2 | |
| SCHEMBL7698646 | 0.83 | RAB9A (0.46) | MAPTALDH1A1L3MBTL1KMT2AMEN1 | |
| SCHEMBL7694233 | 0.83 | SMN1; SMN2 (0.44) | MAPTCYP3A4ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL7695160 | 0.83 | MAPT (0.41) | MAPTCYP3A4ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002064558-A2 | OXAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS CYTOKINE INHIBITORS | SANKYO COMPANY, LIMITED (JP) | 2002-08-22 | — | — | WO | disclosed |