Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | YAP1 | P46937 | 1/20 | 0.43 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.43 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.43 |
| ▸ | PCNA | P12004 | 1/20 | 0.40 |
| ▸ | LIG1 | P18858 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 4/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP14 | P50281 | 2/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7694468 | 0.98 | YAP1 (0.42) | YAP1TEAD4TEAD2PCNALIG1 | |
| SCHEMBL6458680 | 0.78 | ALDH1A1 (0.44) | YAP1TEAD4TEAD2MMP2MMP9 | |
| SCHEMBL576200 | 0.76 | MMP2 (0.55) | YAP1TEAD4TEAD2STSMMP2 | |
| SCHEMBL7364322 | 0.76 | NQO1 (0.52) | — | |
| SCHEMBL28108926 | 0.76 | NQO1 (0.52) | — | |
| SCHEMBL7364325 | 0.76 | NQO1 (0.52) | — | |
| SCHEMBL334384 | 0.75 | SLC6A4 (0.66) | PCNALIG1POLBSLC6A4CYP1A2 | |
| SCHEMBL16767542 | 0.75 | SLC6A4 (0.66) | PCNALIG1POLBSLC6A4CYP1A2 | |
| SCHEMBL334385 | 0.75 | SLC6A4 (0.66) | PCNALIG1POLBSLC6A4CYP1A2 | |
| SCHEMBL28509968 | 0.75 | YAP1 (0.48) | YAP1TEAD4TEAD2STSMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002000622-A2 | AMINOALCOHOL DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-03 | — | — | WO | disclosed |