Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697885 | 0.87 | MTNR1A (0.44) | HSP90AA1MTNR1AMTNR1BALDH1A1CYP1A2 | |
| SCHEMBL7698761 | 0.86 | ALDH1A1 (0.51) | HSP90AA1ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7699488 | 0.73 | ALDH1A1 (0.50) | HSP90AA1MTNR1AMTNR1BALDH1A1CYP1A2 | |
| SCHEMBL7747845 | 0.71 | HTR2A (0.43) | MTNR1AMTNR1BALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL15175477 | 0.70 | NR4A2 (0.65) | ALDH1A1ALOX5HPGDGAALMNA | |
| SCHEMBL7996132 | 0.68 | PLA2G2A (0.47) | MTNR1AMTNR1BALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9427499 | 0.68 | GAA (0.39) | ALDH1A1CYP3A4MAPTALOX5HPGD | |
| SCHEMBL7694116 | 0.68 | PDE10A (0.42) | MTNR1AMTNR1BALDH1A1GAA | |
| SCHEMBL7832340 | 0.67 | TSHR (0.48) | ALDH1A1TSHRMAPTNPSR1GAA | |
| SCHEMBL7290124 | 0.67 | MAPT (0.80) | HSP90AA1ALDH1A1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002020478-A1 | N-BENZYLINDOLE-3-ACETIC ACID DERIVATIVES FOR USE IN THE TREATMENT OF DRUG RESISTAN CANCER | DUBLIN CITY UNIVERSITY (IE) | 2002-03-14 | — | — | WO | disclosed |