Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7324340 | 0.92 | ALDH1A1 (0.61) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL9423504 | 0.85 | LMNA (0.56) | TSHRLMNAMTNR1BMTNR1ACES2 | |
| SCHEMBL2316112 | 0.85 | TSHR (0.54) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL5207507 | 0.81 | L3MBTL1 (0.59) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL10469926 | 0.81 | ALDH1A1 (0.53) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| 1,3-Dimethoxybenzene SCHEMBL27728370 | 0.81 | ALDH1A1 (0.62) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL8395078 | 0.81 | LMNA (0.51) | TSHRLMNAMTNR1BMTNR1ACES2 | |
| SCHEMBL30475592 | 0.80 | SMN1; SMN2 (0.59) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL4427542 | 0.79 | SMN1; SMN2 (0.43) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL5711752 | 0.79 | TDP1 (0.54) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083650-A1 | NOVEL SULFONYLAMINO-PYRIMIDINES | ACTELION PHARMACEUTICALS LTD (CH) | 2002-10-24 | — | — | WO | disclosed |