SCHEMBL7694512

SCHEMBL7694512

CCCCC1=Cc2ccccc2SN=C1CCCC

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.31
GPR84 Q9NQS5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2972479 0.73 GPR84 (0.38) PTPN1GPR84
SCHEMBL10608915 0.68 PTPN1 (0.50) PTPN1
SCHEMBL2871078 0.64 CNR1 (0.43) PTPN1
SCHEMBL10604576 0.63 PTPN1 (0.57) PTPN1
SCHEMBL27744901 0.62 PTPN1 (0.53) PTPN1
SCHEMBL10606408 0.61 PTPN1 (0.60) PTPN1
SCHEMBL27942033 0.61 PTPN1 (0.51) PTPN1
SCHEMBL19279367 0.61
SCHEMBL31511814 0.60 GPR84 (0.31) GPR84
SCHEMBL2957764 0.60 PTPN1 (0.33) PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002008211-A2 BENZOTHIAZEPINES AND THEIR USE AS ANTIHYPERLIPIDEMICS G.D. SEARLE, LLC. (US) 2002-01-31 WO disclosed