⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9391987 | 0.72 | — | — | |
| SCHEMBL10852832 | 0.68 | BCHE (0.34) | — | |
| SCHEMBL9391984 | 0.64 | GABRA1 (0.37) | — | |
| SCHEMBL5637462 | 0.62 | TRPA1 (0.31) | — | |
| SCHEMBL7852096 | 0.61 | ALDH1A1 (0.39) | — | |
| SCHEMBL7694512 | 0.61 | PTPN1 (0.31) | — | |
| SCHEMBL31511814 | 0.60 | GPR84 (0.31) | — | |
| SCHEMBL7851348 | 0.60 | L3MBTL1 (0.35) | — | |
| SCHEMBL7849227 | 0.59 | TRPA1 (0.33) | — | |
| SCHEMBL17701372 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110785173-B | Use of aminoalkyl benzothiazepine derivatives | 怡诺安有限公司 | 2023-01-10 | — | — | CN | disclosed |
| CN-110785173-B | Use of aminoalkyl benzothiazepine derivatives | 怡诺安有限公司 | 2023-01-10 | — | — | CN | disclosed |
| EP-3654987-B1 | USE OF AMINOALKYLBENZOTHIAZEPINE DERIVATIVES | HK INNO N CORP (KR) | 2022-08-31 | — | — | EP | disclosed |
| US-11202783-B2 | Use of aminoalkylbenzothiazepine derivatives | CJ HEALTHCARE CORPORATION (KR) | 2021-12-21 | — | — | US | disclosed |
| US-11202783-B2 | Use of aminoalkylbenzothiazepine derivatives | CJ HEALTHCARE CORPORATION (KR) | 2021-12-21 | — | — | US | disclosed |
| US-11202783-B2 | Use of aminoalkylbenzothiazepine derivatives | CJ HEALTHCARE CORPORATION (KR) | 2021-12-21 | — | — | US | disclosed |
| EP-3654987-A1 | USE OF AMINOALKYLBENZOTHIAZEPINE DERIVATIVES | CJ Healthcare Corporation (KR) | 2020-05-27 | — | — | EP | disclosed |
| EP-3654987-A1 | USE OF AMINOALKYLBENZOTHIAZEPINE DERIVATIVES | CJ Healthcare Corporation (KR) | 2020-05-27 | — | — | EP | disclosed |
| US-20200147101-A1 | USE OF AMINOALKYLBENZOTHIAZEPINE DERIVATIVES | CJ HEALTHCARE CORPORATION (KR) | 2020-05-14 | — | — | US | disclosed |
| US-20200147101-A1 | USE OF AMINOALKYLBENZOTHIAZEPINE DERIVATIVES | CJ HEALTHCARE CORPORATION (KR) | 2020-05-14 | — | — | US | disclosed |
| EP-3210977-B1 | NOVEL AMINOALKYL BENZOTHIAZEPINE DERIVATIVE AND USE THEREOF | CJ HEALTHCARE CORP (KR) | 2019-03-20 | — | — | EP | disclosed |
| WO-2019017724-A1 | USE OF AMINOALKYLBENZOTHIAZEPINE DERIVATIVES | CJ HEALTHCARE CORPORATION (KR) | 2019-01-24 | — | — | WO | disclosed |
| WO-2019017724-A1 | USE OF AMINOALKYLBENZOTHIAZEPINE DERIVATIVES | CJ HEALTHCARE CORPORATION (KR) | 2019-01-24 | — | — | WO | disclosed |
| US-9890129-B2 | Aminoalkylbenzothiazepine derivatives and uses thereof | CJ HEALTHCARE CORPORATION (KR) | 2018-02-13 | — | — | US | disclosed |
| US-9890129-B2 | Aminoalkylbenzothiazepine derivatives and uses thereof | CJ HEALTHCARE CORPORATION (KR) | 2018-02-13 | — | — | US | disclosed |
| US-20170283386-A1 | NOVEL AMINOALKYLBENZOTHIAZEPINE DERIVATIVES AND USES THEREOF | CJ HEALTHCARE CORPORATION (KR) | 2017-10-05 | — | — | US | disclosed |
| US-20170283386-A1 | NOVEL AMINOALKYLBENZOTHIAZEPINE DERIVATIVES AND USES THEREOF | CJ HEALTHCARE CORPORATION (KR) | 2017-10-05 | — | — | US | disclosed |
| EP-3210977-A2 | NOVEL AMINOALKYL BENZOTHIAZEPINE DERIVATIVE AND USE THEREOF | CJ Healthcare Corporation (KR) | 2017-08-30 | — | — | EP | disclosed |
| EP-3210977-A2 | NOVEL AMINOALKYL BENZOTHIAZEPINE DERIVATIVE AND USE THEREOF | CJ Healthcare Corporation (KR) | 2017-08-30 | — | — | EP | disclosed |
| CN-106573902-A | Novel aminoalkylbenzothiazepine derivatives and uses thereof | CJ医药健康株式会社 | 2017-04-19 | — | — | CN | disclosed |