Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 9/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 10/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7696673 | 0.91 | ALDH1A1 (0.58) | TP53SMN1; SMN2TSHRHSD17B10MEN1 | |
| SCHEMBL7702036 | 0.87 | MAPT (0.62) | TP53SMN1; SMN2TSHRHSD17B10MEN1 | |
| SCHEMBL7700431 | 0.81 | TP53 (0.47) | TP53SMN1; SMN2TSHRHSD17B10MEN1 | |
| SCHEMBL7697083 | 0.80 | ALDH1A1 (0.55) | TP53SMN1; SMN2TSHRHSD17B10MEN1 | |
| SCHEMBL6827185 | 0.80 | ALDH1A1 (0.56) | TP53SMN1; SMN2TSHRHSD17B10MEN1 | |
| SCHEMBL25009344 | 0.79 | TP53 (1.00) | TP53SMN1; SMN2TSHRHSD17B10MEN1 | |
| SCHEMBL7700611 | 0.78 | MAPT (0.60) | TP53SMN1; SMN2TSHRHSD17B10MEN1 | |
| SCHEMBL7694685 | 0.77 | MEN1 (1.00) | TP53SMN1; SMN2TSHRHSD17B10MEN1 | |
| SCHEMBL25010121 | 0.77 | ALDH1A1 (1.00) | TP53SMN1; SMN2TSHRHSD17B10MEN1 | |
| SCHEMBL7663107 | 0.77 | ALDH1A1 (0.47) | TP53SMN1; SMN2TSHRHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100842-A1 | SULFONYLOXAZOLAMINES AND THEIR USE AS 5-HT6 LIGANDS | MERCK PATENT GMBH (DE) | 2002-12-19 | — | — | WO | disclosed |