Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TACR2 | P21452 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7524893 | 0.86 | PTPN1 (0.45) | BCHEACHEALDH1A1L3MBTL1KDM4E | |
| SCHEMBL5846091 | 0.85 | BCHE (0.41) | BCHEACHEALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL5846085 | 0.85 | BCHE (0.41) | BCHEACHEALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL7699895 | 0.81 | KMT2A (0.42) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL7571116 | 0.80 | ALDH1A1 (0.36) | ALDH1A1OPRM1 | |
| SCHEMBL7542021 | 0.80 | PTPN1 (0.38) | MEN1KMT2A | |
| SCHEMBL7701621 | 0.80 | HDAC1 (0.36) | ALDH1A1L3MBTL1KDM4EKMT2AHPGD | |
| SCHEMBL7555860 | 0.77 | AKR1C2 (0.37) | BCHEACHEKDM4EMEN1KMT2A | |
| SCHEMBL7703247 | 0.76 | KDM4E (0.49) | ALDH1A1SMN1; SMN2KDM4EMAPTKMT2A | |
| SCHEMBL7564931 | 0.75 | POLB (0.35) | ALDH1A1L3MBTL1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002004458-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 2002-01-17 | — | — | WO | claimed |
| WO-2002004458-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 2002-01-17 | — | — | WO | disclosed |